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## Boron Neutron Capture Therapy: status and Novosibirsk solution

At present, Boron Neutron Capture Therapy (BNCT) is considered to be a promising method for the treatment of tumors. The report presents the basics of BNCT, its development stages, the state of development of accelerator neutron sources for BNCT clinics and describes in detail the Novosibirsk accelerator neutron source. This source is a state-of-the-art device comprised of i) the Vacuum Insulation Tandem Accelerator (VITA) – a new type of charged particle accelerator, ii) an advanced solid lithium target with superior resistance to blistering, and iii) a neutron Beam Shaping Assembly. At VITA characterized by a high acceleration rate of charged particles a stationary proton beam with an energy of 2.3MeV and a current of 9 mA, sufficient for therapy, was obtained. A neutron-producing target optimal for forming an epithermal neutron flux that meets the requirements of BNCT has been developed and experimentally studied. To confirm the required quality of the neutron beam, the effect of neutron radiation on cell cultures and laboratory animals was studied. In the near future, it is planned to prepare a “handmade” Novosibirsk source for conducting therapy and to implement BNCT in 2022. The Novosibirsk source became the prototype source being built for the clinic in Xiamen (China) – one of the first five BNCT clinics. In addition to being used in BNCT, the source was used to determine dangerous impurities in ceramics for ITER and is planned to be used for radiation testing of the optical fiber and photomultiplier for CERN. In the latter case, ...

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## Wave-function Collapse as a Resolution of a Tension between General Relativity and Quantum Theory

Conferenza a cura del Prof. Sir Roger Penrosem (Università di Oxford). Il talk sarà in lingua inglese, adatto ad un pubblico specialistico. Il 25 settembre 2019 il Prof. Sir Roger Penrose, dell’Università di Oxford, terrà una conferenza ai Laboratori Nazionali di Frascati, illustrando la sua visione circa le possibilità di risolvere la tensione tra relatività generale e meccanica quantistica. La conferenza, intitolata “Il collasso della funzione d’onda quale soluzione all’attrito tra Relatività Generale e Teoria Quantistica”, si terrà alle ore 16:15 presso l’Auditorium Bruno Touschek. Il talk è organizzato nell’ambito del workshop “Is Quantum Theory exact? From quantum foundations to quantum applications” che avrà luogo ai LNF tra il 23 e il 27 settembre 2019. Roger Penrose è autore d’importanti contributi alla fisica matematica della relatività generale e della cosmologia. Ha ricevuto numerosi premi e riconoscimenti, tra cui, nel 1988, il Premio Wolf per la fisica assieme a Stephen Hawking per i teoremi sulle singolarità di Penrose–Hawking, la Medaglia Dirac (1989) e la Medaglia Einstein (1990). Ingresso libero su prenotazione Maggiori dettagli relativi al workshop saranno disponibili alla pagina dedicata: https://agenda.infn.it/event/19468/

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## Is Quantum Theory exact? From quantum foundations to quantum applications

The main aim of the “Is Quantum Theory exact? From quantum foundations to quantum applications” Workshop is to discuss theoretical and experimental hot issues related to quantum physics, from foundational issues (such as connection between gravity and quantum physics, collapse models, spin-statistics) to quantum technologies, including new findings and ideas to investigate quantum effects in biological systems. The Workshop is supported by the Museo Storico della Fisica e Centro Studi e Ricerche Enrico Fermi, Roma, by LNF-INFN and by the Foundational Questions Institute, FQXi. Organizers: Catalina Curceanu (LNF-INFN), Chair Pawel Moskal (Jagellionian University, Krakow, Poland) Johann Marton (SMI-Vienna, Austria) Alessandro Scordo (LNF-INFN) Magdalena Skurzok (LNF-INFN) Kristian Piscicchia (Museo Storico della Fisica e Centro Studi e Ricerche Enrico Fermi, Roma and LNF-INFN)   http://www.mdpi.com/journal/entropy Media partner Entropy (ISSN 1099-4300, Impact Factor: 2.419) is an open access journal which maintains a rigorous and fast peer-review system with a median publication time of 44 days from submission to publication online. Since its launch in 1998, it has been fully covered by the leading indexing and abstracting services, including Scopus and SCIE (Web of Science), Google Scholar and MathSciNet. You are welcomed to visit the website http://www.mdpi.com/journal/entropy and to learn more about the journal.

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## A search for the A-prime particle at JLab and a proposal for a Very Asymmetric Collider.

A search was done by using electro-production of a heavy photon (A’) in electron scattering from W nuclei with following decay to an electron-positron pair. The experiment was performed at Hall A of Jefferson Lab using a 2.1 GeV beam and collected statistics for a search sensitivity of 0.1 ppm (relative to the coupling of an EM photon). Such a sensitivity is about 10 times better than known from currently published experiments for the A’ mass near 200 MeV. The experiment and preliminary analysis of the data quality will be presented. In the second part of this talk, I will discuss the search for A’ in an inverse reaction with a positron-electron annihilation which has an important advantage of being independent of the A’ decay. The experiment for the mass range above 70 MeV requires a novel experimental technique because typical colliders with cm energy below 500 MeV have insufficient luminosity. The concept of a Very Asymmetric Collider is based on a low energy electron beam accelerator and a high energy positron storage ring. Such a configuration allows us to boost the luminosity to the level of 10$^{34}$ 1/cm$^2$/s.

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## Logarithmic accuracy of parton showers

We formulate some first fundamental elements of an approach for assessing the logarithmic accuracy of parton-shower algorithms based on two broad criteria: their ability to reproduce the singularity structure of multi-parton matrix elements, and their ability to reproduce logarithmic resummation results. We illustrate our approach by considering properties of two transverse-momentum ordered final-state showers, examining features up to second order in the strong coupling. In particular we identify regions where they fail to reproduce the known singular limits of matrix elements. The characteristics of the shower that are responsible for this also affect the logarithmic resummation accuracies of the shower, both in terms of leading (double) logarithms at subleading colour number and next-to-leading (single) logarithms at leading colour number.

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## Development and testing of particle detector technology for high-energy experiments

Frontier measurements in high-energy heavy-ion collision experiments re- quire challenging developments for detector technologies. For instance, the CERN LHC (Large Hadron Collider) plans of eventually reaching an interac- tion rate of 50 kHz for Pb-Pb collisions require the upgrade of the two ALICE (A Large Ion Collider Experiment) main tracking devices, namely the ITS (In- ner Tracking System) and the TPC (Time Projection Chamber). The ALICE ITS upgrade is primarily focused on improving the performance for detection of heavy-flavor hadrons, and of the thermal photons and low-mass dileptons emitted by the QGP (Quark Gluon Plasma). In order to fulfill such physics programs, the current silicon detectors will be fully replaced with a new, high- resolution, multi-layered, low-material, 12.5 GigaPixel system based on CMOS (Complementary Metal-Oxide-Semiconductor) MAPS (Monolithic Active Pixel Sensors) technology, which is expected to enhance vertexing and tracking at low transverse momenta (pT ), radiation hardness and read-out capabilities. This work presents an overview of MAPS technologies for high-energy experiments, with emphasis on the ITS upgrade case. Keywords: Silicon pixel detectors; MAPS; ITS; High-Energy Heavy-Ion Collisions.

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## Autumn Institute 2019: Directional Sub-GeV Dark Matter Detection

Aim of the meeting: This informal meeting is intended for extensive discussions on directional signals for sub-GeV dark matter particles detection via scattering off electrons. Seminars:   Tuesday 17/09 11:00am:      Elisabetta Baracchini (GSSI,  L’Aquila) “Overview of the International CYGNUS Collaboration Project and of the Italian CYGNO/INITIUM Effort” Tuesday 17/09 14:30pm:     Christopher McCabe  (King’s College,  London) “Overview of the Direct Detection of Light Dark Matter”  Wednesday 18/09 11:00am:      Ciaran A. J. O’Hare (Zaragoza U., Zaragoza) “An Introduction to Directional Detection”  Wednesday 18/09 14:30pm:     Timon Emken (Chalmers University of Technology, Gothenburg) “How Scatterings affect the Dark Matter Velocity Distribution in the Laboratory”

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## Physics and Philosophy of the Future: the Flow of Time between Physics and Metaphysics

Aim of the meeting: The concept of time has always been a topic of great interest and exploration in both physics and philosophy: time scans our experience of the world and is the foundation of our consciousness. We propose an afternoon to discuss the flow of time between physics and metaphysics with researchers active in both fields. In particular, from the philosophical viewpoint, we shall debate the nature of the future as well as possible time travels. Physics wise, it will be investigated the nature of time in relativity and how the quantum theory of gravity and space-time can help the understanding of the fundamental structure of the universe. Program   Thursday July 11   14:30   Samuele Iaquinto (Milan Univ.) “On the Nature of the Future”    15:15   Giuliano Torrengo  (Milan Univ.)  “Time Travels between Physics and Philosophy”   16:00 – 16:30   Coffee Break    16:30   Daniele Oriti  (MPI Potsdam & LMU Munich)  “Time from Classical Relativistic Physics toward Quantum Gravity” 17:30   Discussion

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## PROGETTO ADAMO – Workshop “S. Nicola in Carcere”

Nell’ambito del progetto ADAMO (Tecnologie di Analisi, Diagnostica e Monitoraggio per la Conservazione e Restauro di Beni Culturali) del Distretto Tecnologico Beni e Attività Culturali Centro di Eccellenza della Regione Lazio, sono state realizzate diverse campagne di misura in concomitanza con il cantiere di restauro nella Basilica di San Nicola in Carcere a Roma. Le misure diagnostiche hanno riguardato l’identificazione dei materiali pittorici dell’affresco absidale di Vincenzo Pasqualoni mediante tecniche di spettroscopia e imaging e l’analisi del biodegrado e infiltrazioni d’acqua. Il workshop prevede una parte dedicata alla presentazione dei risultati preliminari ottenuti da vari gruppi di ricerca che hanno preso parte alle misure ed una parte di discussione insieme ai restauratori e agli storici dell’arte. Al termine della riunione sarà possibile visitare il laboratorio di luce di sincrotrone DAFNE-L, facility del progetto ADAMO.

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