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Numerical model fully depicting nanoparticle uptake within brain after ultrasound induced Blood-Brain Barrier opening
Allegra Conti (CEA/NeuroSpin, France)
Low intensity Focused Ultrasound (FUS) combined with microbubbles open the Blood-Brain Barrier (BBB) locally and noninvasively, allowing the passage of nanoparticles into the brain. However, since the quantity of particles that can be delivered with this technique depends on multiple parameters such as tissue properties, particle properties and acoustic parameters, so far a model fully …
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