A whole body of B-meson decays display persistent deviations with respect to the Standard-Model (SM) predictions. These deviations concern coherent sets of data, all of them with two leptons in the final state. Deviations are in the fact that decays to different leptons appear to depart or not from the SM predictions depending on the considered lepton. This can be explained by some new interaction that distinguishes between the lepton species, i.e. one that violates Lepton Universality (LU). After a review of the status and interpretation of data, we explore the question whether models for such beyond-SM effect may leave footprints in the cosmos, e.g. in observables related to Dark Matter or to neutrino fluxes.