The combination of precision space and time information in particle tracking has the capability of transforming how we design experiments,
4D tracking is being considered in the upgrade of the ATLAS, CMS and LHCb experiments at the High-Luminosity LHC, set to start data taking in 2024-25. Regardless of the type of solution chosen, space-time tracking brings benefits to the performance of the detectors by reducing the background and sharpening the resolution; it improves tracking performances and simplifies tracks combinatorics. Space-time tracking also allows investigating new physics channels, for example, it opens up the possibilities of new searches in long-living particles by measuring accurately the time of flight between the production and the decaying vertexes.